gene replacement

[dʒi:n riˈpleismənt]
  • 释义

    [医]基因替代;

数据更新时间:2026-08-19 13:39:47
1、

DNA repair approach has focused on gene targeting or gene replacement whereby the defective gene is removed and a normal gene is inserted at the same position in the chromosome and so it maintains the corrected gene's expression in the natural context.

基因原位修复策略是一种直接的基因疗法,它针对基因缺陷部位进行修复,保持了基因原有的染色质环境,因此是一种理想的靶向性基因治疗方式。

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2、

An A was replaced by a G in codon 38 upstream of the 5 ′ border outside the HMG box of the SRY gene, resulting in the replacement of the amino acid glutamate by glycine.

一个突变发生在SRY基因的5′端HMG盒外的核苷酸第113位腺嘌呤(A)被鸟嘌呤(G)取代,并导致谷氨酸被甘氨酸替换;

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3、

A Primary Study of an Antifreeze Gene Expressed Highly in E. coli and Yeast through Base Replacement

鱼抗冻蛋白在E.coli和Yeast中高效表达的理论初探

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4、

For this purpose, in this study, the candidate pathogenicity-related genes obtained by different approaches were compared and the functions of some candidate genes were validated by knocking them out using the method of target gene replacement.

为此,本研究对不同技术获得的稻瘟菌候选致病基因进行比较,并采用基因敲除的方法对一些候选基因的功能进行验证。

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5、

selective production of clavulanic acid by lat gene replacement in streptomyces clavuligerus

棒状链霉菌中lat基因的置换与克拉维酸的选择性生产

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6、

For this purpose, in this study, the candidate pathogenicity-related genes obtained by different approaches were compared and the functions of some candidate genes were validated by knocking them out using the method of target gene replacement.

为此,本研究对不同技术获得的稻瘟菌候选致病基因进行比较,并采用基因敲除的方法对一些候选基因的功能进行验证。

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